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Antibody-drug Conjugate/ADC Related
HDAC6
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Product name : Trichostatin A(TSA)
Item : CR1132
CAS : 58880-19-6
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| Details: |
Description of:Trichostatin A(TSA)
Trichostatin A /TSA, an antifungal antibiotic produced by Streptomyces hygroscopicus (1], Trichostatin A /TSA is a potent and specific inhibitor of histone deacetylase (HDAC). HDAC is overexpressed in a variety of cancers and is closely correlated with oncogenic factors. Trichostatin A /TSA is active at a nanomolar concentration and causes accumulation of highly acetylated histone molecules in mammalian cells [2]. Trichostatin A /TSA suppresses the activity of HDAC leading to an increase in histone acetylation. This histone acetylation induces an enhancement of the expression of specific genes that elicit extensive cellular morphologic and metabolic changes, such as growth arrest, differentiation and apoptosis. Theoretical analysis:Trichostatin A(TSA) M.Wt: 302.4 Formula: C17H22N2O3 Solubility: Soluble in MeOH or DMSO Purity: 98% Optical purity 98% Storage: -20C 2 years CAS No: 58880-19-6 Availability and price: Pakage：10mg/25mg/100mg/250mg/500mg/1g/5g Stock : in stock We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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