Products Category
Antibody-drug Conjugate/ADC Related
PDE
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Description of:AZ3146
Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembly checkpoint. Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores Theoretical analysis:AZ3146 M.Wt:452.55 Formula:C24H32N6O3 Solubility:Soluble to 25 mM in DMSO and to 75 mM in ethanol Purity:>99 % Storage:Store at +4°C CAS No: 1124329-14-1 Availability and price:AZ3146 Pakage：25mg/50mg/100mg/250mg/500mg/1g/5g Stock : in stock We offer significant discount for larger quantity order. For quotation, question, and order, please send email to : sales@chemrenpharm.com Quality control data: Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Product will be shipped with supporting analytical data. Fast delivery about 4-5 working days |
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