Chemren Bio-Engineering Co., Ltd.

Description of:TDZD-8/ GSK-3ß Inhibitor 
Glycogen Synthase Kinase-3ß is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3ß ( IC50 =2nM). Binds to the active site of GSK-3ß. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).

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Theoretical analysis:TDZD-8/ GSK-3ß Inhibitor 

Chemical Name:   4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione

Synonyms:   GSK-3ß Inhibitor I, TDZD-8

CAS Number:   327036-89-5

Possible CAS Number:   NA

Mol. Formula:   C10H10N2O2S

Appearance:   White Solid

Melting Point:   60-61°C

Mol. Weight:   222.26

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Availability and price:TDZD-8/ GSK-3ß Inhibitor 
Pakage：25mg/50mg/100mg/250mg/500mg/1g/5g
Stock : in stock
We offer significant discount for larger quantity order.
For quotation, question, and order, please send email to : sales@chemrenpharm.com

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Quality control data:
Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Product will be shipped with supporting analytical data.
Fast delivery about 4-5 working days

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