常州市存仁生物工程有限公司

JNJ38877605

JNJ38877605

Description of:JNJ38877605
JNJ-38877605 is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antineoplas...
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Tivantinib(ARQ197)

Tivantinib(ARQ197)

Description of:Tivantinib(ARQ197)
Exposure to ARQ197(Tivantinib) resulted in the inhibition of proliferation of c-Met–expressing cancer c...
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Crizotinib

Crizotinib

Description of:Crizotinib
PF-2341066(Crizotinib) showed similar potency against c-Met phosphorylation in mIMCD3 mouse (IC50, 5 nmol/L) or MDCK ...
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Masitinib

Masitinib

Description of:Masitinib
Masitinib inhibits wild-type human and murine KIT in vitro with an IC50 of approximately 200 nM, and administered PO m...
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CHIR-258(Dovitinib)|多韦替尼

CHIR-258(Dovitinib)|多韦替尼

Description of:CHIR-258(Dovitinib)
CHIR-258 was highly potent against FLT3 (1 nmol/L) with nanomolar activity against c-KIT (2 nmol/L), VEGFR1/...
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Imatinib Mesylate

Imatinib Mesylate

Description of:Imatinib Mesylate
Imatinib inhibits EOL-1 cell viability (IC50 = 0.5 nM), phosphorylation of a fusion protein (IC50 = 30 nM), an...
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NVP-BHG712

NVP-BHG712

Description of:NVP-BHG712
NVP-BHG712 inhibits VEGF driven angiogenesis. In a panel of more than 40 in vitro kinase assays, NVP-BHG712 showed ex...
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NVP-TAE684

NVP-TAE684

Description of:NVP-TAE684
NVP-TAE684 is a highly potent and selective smallmolecule ALK inhibitor, which blocked the growth of ALCL-derived and...
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SB525334

SB525334

Description of:SB525334
SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50=14.3 nM).&...
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CH5424802

CH5424802

Description of:CH5424802
CH5424802 is a potent, selective, and orally available ALK inhibitor. which with a unique chemical scaffold, showing p...
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