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Vatalanib Dihydrochloride
Description of:Vatalanib Dihydrochloride
Vatalanib is a potent, selective, orally active inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1...
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CP-673451
Description of:CP-673451
In a sponge angiogenesis model, CP-673451 inhibited 70% of PDGF-BB-stimulated angiogenesis at a dose of 3 mg/kg ...
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KRN633
Description of:KRN633
KRN633 inhibits PDGFR-α and c-Kit at higher concentrations only (IC50 = 0.97 µM and 4.33 µM, respective...
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Cabozantinib|卡博替尼
Description of:Cabozantinib
Cabozantinib was granted orphan-drug status by the FDA in January 2011.It is currently in a number of clinical tria...
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Pazopanib(帕唑帕尼)
Theoretical analysis:Pazopanib(GW-786034)
M.Wt: 473.98
Formula: C21H23N7O2S.HCL
Solubility: Soluble in DMSO at 10 mmol/L
P...
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BAY 61-3606
Description of:BAY 61-3606
BAY 61-3606 (BAY 61-3606) is a cell-permeable imidazopyrimidine compound that acts as a potent, ATP-competitive, rev...
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R788|Fostamatinib
Description of:R788|Fostamatinib
R935788 (Fostamatinib disodium) has shown clinical activity in heavily pre-treated NHL and CLL patients, exhib...
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Bafetinib
Description of:Bafetinib
Bafetinib (INNO-406) is an orally available, dual Abl/Lyn kinase inhibitor (cell IC50 : 11 ~ 22 nM).
Theoreti...
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Fingolimod(FTY720)
Description of:Fingolimod(FTY720)
Fingolimod is Src-bcr-Abl Inhibitor & S1P receptor agonist with IC50 of 0.137, 10.98 nM for (S)- and (R)-...
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Saracatinib
Description of:Saracatinib
AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of Focal adhesion kinas...
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Antibody-drug Conjugate/ADC Related
Trk Receptor
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